Sefton Council has announced that the Bellway Homes are set to commence work at the Klondyke Development on Monday, March 13.
The major milestone will see the construction of 142 homes on the site which has already been cleared and prepared for redevelopment.
Cllr Trish Hardy, Cabinet Member for Communities and Housing, said: “I am delighted that work is finally set to start on this development, bringing much needed quality housing to the borough.
“Importantly this development will have wider reaching impact on regeneration with increased footfall for local shops and businesses.
“The new estate which has already been finished is an example of the future of the Klondyke and the future of Bootle. I look forward to seeing this final project completed.”